Sodium/myo-inositol cotransporter

SLC5A3
Identifiers
Aliases	SLC5A3, BCW2, SMIT, SMIT1, SMIT2, solute carrier family 5 member 3
External IDs	OMIM: 600444; MGI: 1858226; HomoloGene: 31412; GeneCards: SLC5A3; OMA:SLC5A3 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	34,106,260 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	91,884,361 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; Epithelium of choroid plexus; ; tibia; ; cartilage tissue; ; retinal pigment epithelium; ; trabecular bone; ; trigeminal ganglion; ; spinal ganglia; ; visceral pleura; ; mucosa of paranasal sinus;
	Top expressed in
	vestibular membrane of cochlear duct; ; ciliary body; ; iris; ; Epithelium of choroid plexus; ; vestibular sensory epithelium; ; calvaria; ; sciatic nerve; ; pineal gland; ; endothelial cell of lymphatic vessel; ; retinal pigment epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	myo-inositol:sodium symporter activity; symporter activity; transmembrane transporter activity; glucose:sodium symporter activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	regulation of respiratory gaseous exchange; peripheral nervous system development; ion transport; sodium ion transport; inositol metabolic process; transmembrane transport; myo-inositol transport; glucose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6526
	53881
	ENSG00000198743
	ENSMUSG00000089774
	P53794
	Q9JKZ2
	NM_006933
	NM_017391
	n/a
	NP_059087
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.

Expression of the myo-inositol transport protein is regulated by osmotic stress.