Sodium- and chloride-dependent glycine transporter 1

SLC6A9
Identifiers
Aliases	SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG
External IDs	OMIM: 601019; MGI: 95760; HomoloGene: 5050; GeneCards: SLC6A9; OMA:SLC6A9 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	44,031,467 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	117,732,395 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; skin of leg; ; skin of abdomen; ; right adrenal gland; ; stromal cell of endometrium; ; left adrenal gland; ; right adrenal cortex; ; left adrenal cortex; ; mucosa of transverse colon; ; mucosa of esophagus;
	Top expressed in
	neural layer of retina; ; secondary oocyte; ; retinal pigment epithelium; ; fetal liver hematopoietic progenitor cell; ; deep cerebellar nuclei; ; primary oocyte; ; zygote; ; lumbar subsegment of spinal cord; ; Medulla Oblongata; ; dorsal tegmental nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neurotransmitter:sodium symporter activity; amino acid:sodium symporter activity; glycine transmembrane transporter activity; symporter activity; glycine:sodium symporter activity; transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; presynapse; integral component of plasma membrane; postsynaptic density; integral component of synaptic vesicle membrane; asymmetric synapse; hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; integral component of postsynaptic membrane; integral component of presynaptic membrane;
Biological process	amino acid transmembrane transport; neurotransmitter transport; amino acid transport; glycine secretion, neurotransmission; glycine transport; organic acid transmembrane transport; transmembrane transport; regulation of synaptic transmission, glycinergic;
	Sources:Amigo / QuickGO
Orthologs
	6536
	14664
	ENSG00000196517
	ENSMUSG00000028542
	P48067
	P28571
NM_001024845; NM_001261380; NM_006934; NM_201649; NM_001328626;
	NM_001328627; NM_001328628; NM_001328629; NM_001328630
	NM_008135; NM_001355175; NM_001369016; NM_001369017
NP_001020016; NP_001248309; NP_001315555; NP_001315556; NP_001315557;
	NP_001315558; NP_001315559; NP_008865; NP_964012
	NP_032161; NP_001342104; NP_001355945; NP_001355946
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium- and chloride-dependent glycine transporter 1, also known as glycine transporter 1, is a protein that in humans is encoded by the SLC6A9 gene which is promising therapeutic target for treatment of diabetes and obesity.