SLC8B1

SLC8B1
Identifiers
Aliases	SLC8B1, NCKX6, NCLX, SLC24A6, solute carrier family 8 member B1
External IDs	OMIM: 609841; MGI: 2180781; HomoloGene: 41602; GeneCards: SLC8B1; OMA:SLC8B1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	113,359,493 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	120,672,089 bp
RNA expression pattern
	Top expressed in
	left adrenal cortex; ; right adrenal gland; ; right adrenal cortex; ; left ovary; ; right ovary; ; spleen; ; mucosa of transverse colon; ; sural nerve; ; granulocyte; ; epithelium of colon;
	Top expressed in
	granulocyte; ; stroma of bone marrow; ; decidua; ; left lobe of liver; ; lip; ; tibiofemoral joint; ; yolk sac; ; left colon; ; gastrula; ; mesenteric lymph nodes;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; identical protein binding; antiporter activity; calcium:cation antiporter activity; calcium:sodium antiporter activity; calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential;
Cellular component	integral component of membrane; membrane; plasma membrane; mitochondrial crista; mitochondrion; integral component of mitochondrial membrane; sarcolemma; mitochondrial inner membrane;
Biological process	sodium ion transmembrane transport; regulation of cytosolic calcium ion concentration; glucose homeostasis; response to stimulus; regulation of insulin secretion; sodium ion transport; ion transport; calcium ion transmembrane transport; regulation of cardiac muscle cell membrane potential; calcium ion transport; transmembrane transport; mitochondrial calcium ion transmembrane transport; mitochondrial calcium ion homeostasis; calcium export from the mitochondrion; regulation of lymphocyte chemotaxis; regulation of store-operated calcium entry;
	Sources:Amigo / QuickGO
Orthologs
	80024
	170756
	ENSG00000089060
	ENSMUSG00000032754
	Q6J4K2
	Q925Q3
	NM_024959; NM_001330466; NM_001358345
	NM_001177594; NM_001177595; NM_133221
	NP_001317395; NP_079235; NP_001345274
	NP_001171065; NP_001171066; NP_573484
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 is a protein that in humans is encoded by the SLC8B1 gene.