SLFN11

SLFN11
Identifiers
Aliases	SLFN11, SLFN8/9, schlafen family member 11
External IDs	OMIM: 614953; MGI: 2672859; HomoloGene: 89175; GeneCards: SLFN11; OMA:SLFN11 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	35,373,701 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	82,911,636 bp
RNA expression pattern
	Top expressed in
	monocyte; ; Achilles tendon; ; sural nerve; ; bone marrow cells; ; right lobe of thyroid gland; ; left uterine tube; ; left lobe of thyroid gland; ; granulocyte; ; appendix; ; upper lobe of left lung;
	Top expressed in
	spleen; ; granulocyte; ; thymus; ; bone marrow; ; embryo; ; ovary; ; embryo; ; zone of skin; ; jejunum; ; liver;
	More reference expression data
	n/a
Gene ontology
Molecular function	tRNA binding; nucleotide binding; ATP binding; RNA binding; protein binding; ATPase activity; helicase activity; hydrolase activity;
Cellular component	aggresome; nucleus; nucleoplasm; cytosol; site of DNA damage; chromosome;
Biological process	negative regulation of G1/S transition of mitotic cell cycle; defense response to virus; immune system process; negative regulation of DNA replication; positive regulation of cell death; replication fork arrest; cellular response to DNA damage stimulus;
	Sources:Amigo / QuickGO
Orthologs
	91607
	276950
	ENSG00000172716
	ENSMUSG00000035208
	Q7Z7L1
	B1ARD8
NM_001104587; NM_001104588; NM_001104589; NM_001104590; NM_152270;
	NM_001376007; NM_001376008; NM_001376009; NM_001376010; NM_001376011; NM_001376012; NM_001387158; NM_001387159; NM_001387160; NM_001387161; NM_001387162; NM_001387163
	NM_001167743; NM_181545
NP_001098057; NP_001098058; NP_001098059; NP_001098060; NP_689483;
	NP_001362936; NP_001362937; NP_001362938; NP_001362939; NP_001362940; NP_001362941
	NP_001161215; NP_853523
	Wikidata
View/Edit Human	View/Edit Mouse

Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene.