SLIT1

SLIT1
Identifiers
Aliases	SLIT1, MEGF4, SLIL1, SLIT-1, SLIT3, slit guidance ligand 1
External IDs	OMIM: 603742; MGI: 1315203; HomoloGene: 2302; GeneCards: SLIT1; OMA:SLIT1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	97,185,959 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	41,732,104 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; orbitofrontal cortex; ; Region I of hippocampus proper; ; Brodmann area 10; ; Brodmann area 23; ; Brodmann area 46; ; entorhinal cortex; ; superior frontal gyrus; ; pancreatic ductal cell; ; frontal pole;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; superior frontal gyrus; ; urethra; ; male urethra; ; hippocampus proper; ; stellate reticulum; ; enamel knot; ; ventricular zone; ; Rostral migratory stream;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; Roundabout binding; heparin binding;
Cellular component	extracellular region; extracellular space; intracellular anatomical structure;
Biological process	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration; cell differentiation; neuron projection morphogenesis; dorsal/ventral axon guidance; negative chemotaxis; axonogenesis; negative regulation of synapse assembly; nervous system development; telencephalon cell migration; multicellular organism development; forebrain morphogenesis; tangential migration from the subventricular zone to the olfactory bulb; olfactory bulb development; motor neuron axon guidance; axon extension involved in axon guidance; retinal ganglion cell axon guidance; axon guidance; nuclear migration;
	Sources:Amigo / QuickGO
Orthologs
	6585
	20562
	ENSG00000187122
	ENSMUSG00000025020
	O75093
	Q80TR4
	NM_003061
	NM_015748
	NP_003052
	NP_056563
	Wikidata
View/Edit Human	View/Edit Mouse

Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene.