SLURP1

SLURP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MUP, 2MUO
Identifiers
Aliases	SLURP1, ANUP, ARS, ArsB, LY6LS, MDM, secreted LY6/PLAUR domain containing 1, LY6-MT
External IDs	OMIM: 606119; MGI: 1930923; HomoloGene: 10710; GeneCards: SLURP1; OMA:SLURP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	142,742,406 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	74,599,883 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; mucosa of pharynx; ; human penis; ; skin of arm; ; skin of abdomen; ; oral cavity; ; skin of thigh; ; body of tongue; ; vulva; ; gums;
	Top expressed in
	lip; ; skin of external ear; ; esophagus; ; pyloric antrum; ; mucous cell of stomach; ; cornea; ; cervix; ; ankle; ; spermatocyte; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; acetylcholine receptor activator activity; protein binding;
Cellular component	extracellular exosome; extracellular space; extracellular region;
Biological process	cell adhesion; negative regulation of keratinocyte proliferation; neuromuscular process controlling posture; locomotory behavior; cell activation; negative regulation of cell population proliferation; negative regulation of cell migration; urokinase plasminogen activator signaling pathway; positive regulation of signaling receptor activity; regulation of signaling receptor activity; regulation of neurotransmitter receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	57152
	57277
	ENSG00000126233
	ENSMUSG00000022596
	P55000
	Q9Z0K7
	NM_020427
	NM_020519
	NP_065160
	NP_065265
	Wikidata
View/Edit Human	View/Edit Mouse

Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene. It exerts anti-inflammatory effects, acts as a tumor suppressor, and antagonizes nicotinic receptors.