SMAP1

SMAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CRR
Identifiers
Aliases	SMAP1, SMAP-1, small ArfGAP 1
External IDs	OMIM: 611372; MGI: 2138261; HomoloGene: 134676; GeneCards: SMAP1; OMA:SMAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	70,862,011 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	23,961,398 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; mucosa of sigmoid colon; ; oral cavity; ; Pons; ; mucosa of pharynx; ; duodenum; ; skin of thigh; ; skin of hip; ; islet of Langerhans; ; ganglionic eminence;
	Top expressed in
	blood; ; genital tubercle; ; tail of embryo; ; seminiferous tubule; ; spermatid; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; superior frontal gyrus; ; calvaria; ; gastrula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	clathrin binding; metal ion binding; GTPase activator activity;
Cellular component	cytoplasm; plasma membrane; membrane;
Biological process	positive regulation of GTPase activity; regulation of clathrin-dependent endocytosis; positive regulation of erythrocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	60682
	98366
	ENSG00000112305
	ENSMUSG00000026155
	Q8IYB5
	Q91VZ6
	NM_001044305; NM_001281439; NM_001281440; NM_021940
	NM_001290683; NM_028534; NM_001357395
	NP_001037770; NP_001268368; NP_001268369; NP_068759
	NP_001277612; NP_082810; NP_001344324
	Wikidata
View/Edit Human	View/Edit Mouse

Stromal membrane-associated protein 1 is a protein that in humans is encoded by the SMAP1 gene.

The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms.