SMARCA5

SMARCA5
Identifiers
Aliases	SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
External IDs	OMIM: 603375; MGI: 1935129; HomoloGene: 55764; GeneCards: SMARCA5; OMA:SMARCA5 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	143,557,486 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	81,466,126 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; Achilles tendon; ; buccal mucosa cell; ; ganglionic eminence; ; Epithelium of choroid plexus; ; corpus callosum; ; superior vestibular nucleus; ; subthalamic nucleus; ; epithelium of nasopharynx; ; gonad;
	Top expressed in
	tail of embryo; ; abdominal wall; ; Gonadal ridge; ; mandibular prominence; ; maxillary prominence; ; cumulus cell; ; ventricular zone; ; epiblast; ; migratory enteric neural crest cell; ; superior cervical ganglion;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; helicase activity; histone binding; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; protein binding; nucleic acid binding; nucleosome binding; hydrolase activity; DNA binding; ATP binding; ATPase activity; DNA-binding transcription factor activity, RNA polymerase II-specific; ATP-dependent activity, acting on DNA;
Cellular component	RSF complex; nuclear replication fork; nucleoplasm; condensed chromosome; nucleus; fibrillar center; NURF complex; chromatin silencing complex; ISWI-type complex;
Biological process	epigenetic maintenance of chromatin in transcription-competent conformation; regulation of transcription by RNA polymerase II; CENP-A containing chromatin assembly; DNA-templated transcription, initiation; nucleosome assembly; chromatin remodeling; rDNA heterochromatin assembly; positive regulation of transcription, DNA-templated; cellular response to leukemia inhibitory factor; chromatin organization; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8467
	93762
	ENSG00000153147
	ENSMUSG00000031715
	O60264
	Q91ZW3
	NM_003601
	NM_053124
	NP_003592
	NP_444354
	Wikidata
View/Edit Human	View/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein that in humans is encoded by the SMARCA5 gene.