SMARCAD1

SMARCAD1
Identifiers
Aliases	SMARCAD1, ADERM, ETL1, HEL1, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1, BASNS, HRZ
External IDs	OMIM: 612761; MGI: 95453; HomoloGene: 5301; GeneCards: SMARCAD1; OMA:SMARCAD1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	94,291,292 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	65,093,045 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; tibia; ; secondary oocyte; ; pancreatic epithelial cell; ; ventricular zone; ; Achilles tendon; ; testicle; ; skin of thigh; ; visceral pleura; ; parietal pleura;
	Top expressed in
	genital tubercle; ; morula; ; tail of embryo; ; ganglionic eminence; ; ventricular zone; ; medial ganglionic eminence; ; blastocyst; ; superior cervical ganglion; ; zygote; ; abdominal wall;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; nucleotide binding; helicase activity; protein binding; nucleic acid binding; hydrolase activity; ATP binding; chromatin binding; ATP-dependent activity, acting on DNA;
Cellular component	site of double-strand break; nuclear matrix; nuclear replication fork; nucleoplasm; chromosome; heterochromatin; nucleus;
Biological process	regulation of DNA recombination; histone H3 deacetylation; chromatin remodeling; DNA double-strand break processing; nucleotide metabolic process; cellular response to DNA damage stimulus; positive regulation of transcription, DNA-templated; chromosome separation; histone H4 deacetylation; protein homooligomerization; DNA repair; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	56916
	13990
	ENSG00000163104
	ENSMUSG00000029920
	Q9H4L7
	Q04692
	NM_001128429; NM_001128430; NM_001254949; NM_020159
	NM_001253392; NM_007958; NM_001355248; NM_001355249; NM_001355250
NP_001121901; NP_001121902; NP_001241878; NP_064544; NP_001362784;
	NP_001362785; NP_001362786; NP_001362787; NP_001362788
	NP_001240321; NP_031984; NP_001342177; NP_001342178; NP_001342179
	Wikidata
View/Edit Human	View/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 is a protein that in humans is encoded by the SMARCAD1 gene.

Proper expression of SMARCAD1 may be important to fingerprint development, and the disruption of its expression is believed to cause adermatoglyphia, the absence of fingerprints.