SMARCD1

SMARCD1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UHR
Identifiers
Aliases	SMARCD1, BAF60A, CRACD1, Rsc6p, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, CSS11
External IDs	OMIM: 601735; MGI: 1933623; HomoloGene: 20670; GeneCards: SMARCD1; OMA:SMARCD1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	50,100,707 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	99,611,872 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right ovary; ; cardia; ; right hemisphere of cerebellum; ; body of uterus; ; left ovary; ; granulocyte;
	Top expressed in
	superior frontal gyrus; ; ventricular zone; ; epiblast; ; primary visual cortex; ; tail of embryo; ; neural tube; ; dentate gyrus of hippocampal formation granule cell; ; genital tubercle; ; olfactory tubercle; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	molecular adaptor activity; transcription coactivator activity; chromatin binding; protein binding; signaling receptor binding;
Cellular component	npBAF complex; nBAF complex; nucleus; nucleoplasm; intracellular membrane-bounded organelle; SWI/SNF complex;
Biological process	regulation of transcription by RNA polymerase II; chromatin remodeling; nucleosome disassembly; cellular response to fatty acid; nervous system development; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	6602
	83797
	ENSG00000066117
	ENSMUSG00000023018
	Q96GM5
	Q61466
	NM_003076; NM_139071
	NM_031842
	NP_003067; NP_620710
	NP_114030
	Wikidata
View/Edit Human	View/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 is a protein that in humans is encoded by the SMARCD1 gene.

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene.