SMARCD2

SMARCD2
Identifiers
Aliases	SMARCD2, BAF60B, CRACD2, Rsc6p, PRO2451, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2, SGD2
External IDs	OMIM: 601736; MGI: 1933621; HomoloGene: 20671; GeneCards: SMARCD2; OMA:SMARCD2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	63,843,065 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	106,163,798 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; body of pancreas; ; gastric mucosa; ; body of stomach; ; minor salivary glands; ; left uterine tube; ; ectocervix; ; cerebellar hemisphere; ; tibial nerve;
	Top expressed in
	Ileal epithelium; ; conjunctival fornix; ; renal corpuscle; ; medullary collecting duct; ; hair follicle; ; Paneth cell; ; lacrimal gland; ; condyle; ; fossa; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; nucleosomal DNA binding; transcription coactivator activity; protein binding;
Cellular component	SWI/SNF complex; nucleus; nucleoplasm; protein-containing complex;
Biological process	regulation of transcription by RNA polymerase II; chromatin remodeling; nucleosome disassembly; regulation of transcription, DNA-templated; transcription, DNA-templated; chromatin organization; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	6603
	83796
	ENSG00000108604
	ENSMUSG00000078619
	Q92925
	Q99JR8
	NM_001098426; NM_003077; NM_001330439; NM_001330440
	NM_001130187; NM_031878
	NP_001091896; NP_001317368; NP_001317369
	NP_001123659; NP_114084
	Wikidata
View/Edit Human	View/Edit Mouse

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 is a protein in humans that is encoded by the SMARCD2 gene.

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein.