SMC6

SMC6
Identifiers
Aliases	SMC6, SMC-6, SMC6L1, hstructural maintenance of chromosomes 6
External IDs	OMIM: 609387; MGI: 1914491; HomoloGene: 41575; GeneCards: SMC6; OMA:SMC6 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	17,800,242 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	11,369,786 bp
RNA expression pattern
	Top expressed in
	sperm; ; secondary oocyte; ; Achilles tendon; ; retinal pigment epithelium; ; left testis; ; right testis; ; testicle; ; corpus epididymis; ; Epithelium of choroid plexus; ; ventricular zone;
	Top expressed in
	tail of embryo; ; genital tubercle; ; primitive streak; ; Rostral migratory stream; ; spermatocyte; ; yolk sac; ; ventricular zone; ; migratory enteric neural crest cell; ; blood; ; spermatid;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; ubiquitin protein ligase binding;
Cellular component	site of double-strand break; PML body; sex chromosome; nuclear speck; Smc5-Smc6 complex; intracellular anatomical structure; nucleoplasm; chromosome; telomere; interchromatin granule; nucleus;
Biological process	DNA recombination; cellular response to DNA damage stimulus; telomere maintenance via recombination; cellular senescence; positive regulation of chromosome segregation; double-strand break repair via homologous recombination; DNA repair;
	Sources:Amigo / QuickGO
Orthologs
	79677
	67241
	ENSG00000163029
	ENSMUSG00000020608
	Q96SB8
	Q924W5
	NM_001142286; NM_024624
	NM_025695; NM_001324476; NM_001361252
	NP_001135758; NP_078900
	NP_001311405; NP_079971; NP_001348181
	Wikidata
View/Edit Human	View/Edit Mouse

Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene.