SMG1

SMG1
Identifiers
Aliases	SMG1, 61E3.4, ATX, LIP, nonsense mediated mRNA decay associated PI3K related kinase, SMG1 nonsense mediated mRNA decay associated PI3K related kinase
External IDs	OMIM: 607032; MGI: 1919742; HomoloGene: 56697; GeneCards: SMG1; OMA:SMG1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	18,926,408 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	117,842,893 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; sural nerve; ; epithelium of colon; ; skin of hip; ; Achilles tendon; ; epithelium of nasopharynx; ; parietal pleura; ; mucosa of sigmoid colon; ; visceral pleura; ; jejunal mucosa;
	Top expressed in
	tail of embryo; ; genital tubercle; ; lobe of cerebellum; ; cerebellar vermis; ; mesenteric lymph nodes; ; medullary collecting duct; ; Rostral migratory stream; ; renal corpuscle; ; neural layer of retina; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	telomeric DNA binding; ATP binding; protein kinase activity; protein binding; kinase activity; metal ion binding; nucleotide binding; transferase activity; protein serine/threonine kinase activity; RNA binding;
Cellular component	nucleus; cytosol; cytoplasm; nucleoplasm;
Biological process	response to stress; mRNA export from nucleus; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; peptidyl-serine phosphorylation; phosphatidylinositol phosphate biosynthetic process; cellular response to DNA damage stimulus; protein autophosphorylation; phosphorylation; regulation of telomere maintenance; DNA repair; regulation of response to DNA damage stimulus; protein phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	23049
	233789
	ENSG00000157106
	ENSMUSG00000030655
	Q96Q15
	Q8BKX6
	NM_015092
	NM_001031814; NM_177180
	NP_055907
	NP_001026984
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase SMG1 is an enzyme that in humans is encoded by the SMG1 gene. SMG1 belongs to the phosphatidylinositol 3-kinase-related kinase protein family.