SMS (gene)

SMS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3C6K, 3C6M
Identifiers
Aliases	SMS, MRSR, SPMSY, SRS, SpS, spermine synthase, MRXSSR
External IDs	OMIM: 300105; MGI: 3705601; HomoloGene: 88709; GeneCards: SMS; OMA:SMS - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	21,994,837 bp
RNA expression pattern
	Top expressed in
	placenta; ; ganglionic eminence; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; human kidney; ; endometrium; ; ventricular zone; ; islet of Langerhans; ; ovary;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; spermine synthase activity;
Cellular component	cytosol; extracellular exosome;
Biological process	spermine biosynthetic process; spermine metabolic process; polyamine biosynthetic process; methionine metabolic process; polyamine metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6611
	671878
	ENSG00000102172
	n/a
	P52788
	P97355
	NM_001258423; NM_004595
	XM_001473434
	NP_001245352; NP_004586
	NP_033240; NP_001346114
	Wikidata
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Spermine synthase is an enzyme that in humans is encoded by the SMS gene. The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes a ubiquitous enzyme of polyamine metabolism.