Small nuclear ribonucleoprotein D2

SNRPD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B34, 3CW1, 3PGW, 3S6N, 4F7U, 4PJO, 4V98, 4WZJ, 3JCR
Identifiers
Aliases	SNRPD2, SMD2, SNRPD1, Sm-D2, Small nuclear ribonucleoprotein D2, small nuclear ribonucleoprotein D2 polypeptide
External IDs	OMIM: 601061; MGI: 98345; HomoloGene: 3381; GeneCards: SNRPD2; OMA:SNRPD2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	45,692,569 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	18,887,467 bp
RNA expression pattern
	Top expressed in
	beta cell; ; embryo; ; corpus epididymis; ; oral cavity; ; left ovary; ; ganglionic eminence; ; tail of epididymis; ; caput epididymis; ; superficial temporal artery; ; vulva;
	Top expressed in
	yolk sac; ; synovial joint; ; urinary bladder; ; ankle joint; ; embryo; ; ventricular zone; ; embryo; ; lens; ; epiblast; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; RNA binding; U1 snRNP binding;
Cellular component	cytoplasm; SMN-Sm protein complex; cytosol; catalytic step 2 spliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP; U12-type spliceosomal complex; U2 snRNP; nucleoplasm; methylosome; precatalytic spliceosome; small nuclear ribonucleoprotein complex; pICln-Sm protein complex; spliceosomal complex; U4 snRNP; extracellular exosome; nucleus; U1 snRNP; U2-type precatalytic spliceosome; U2-type catalytic step 2 spliceosome;
Biological process	mRNA splicing, via spliceosome; mRNA processing; spliceosomal snRNP assembly; spliceosomal complex assembly; RNA splicing; import into nucleus;
	Sources:Amigo / QuickGO
Orthologs
	6633
	107686
	ENSG00000125743
	ENSMUSG00000040824
	P62316
	P62317
	NM_004597; NM_177542; NM_001369751; NM_001369752; NM_001384647
	NM_026943
	NP_004588; NP_808210; NP_001356680; NP_001356681
	NP_081219
	Wikidata
View/Edit Human	View/Edit Mouse

Small nuclear ribonucleoprotein Sm D2 is a protein that in humans is encoded by the SNRPD2 gene. It belongs to the small nuclear ribonucleoprotein core protein family, and is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.