SNTG1

SNTG1
Identifiers
Aliases	SNTG1, G1SYN, SYN4, syntrophin gamma 1
External IDs	OMIM: 608714; MGI: 1918346; HomoloGene: 56834; GeneCards: SNTG1; OMA:SNTG1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	50,796,692 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	9,299,878 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; primary visual cortex; ; middle temporal gyrus; ; ventricular zone; ; testicle; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; nucleus accumbens; ; prefrontal cortex; ; caudate nucleus;
	Top expressed in
	lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; spermatid; ; primary visual cortex; ; superior frontal gyrus; ; neural layer of retina; ; facial motor nucleus; ; embryo; ; cerebellar cortex; ; hippocampus proper;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; protein C-terminus binding; structural molecule activity;
Cellular component	cytoplasm; ruffle membrane; syntrophin complex; cytoskeleton; nucleus; dystrophin-associated glycoprotein complex;
Biological process	cell communication;
	Sources:Amigo / QuickGO
Orthologs
	54212
	71096
	ENSG00000147481
	ENSMUSG00000025909
	Q9NSN8
	Q925E1
NM_001287813; NM_001287814; NM_018967; NM_001321773; NM_001321775;
	NM_001321776; NM_001321777; NM_001321778
	NM_001290390; NM_001290392; NM_001290393; NM_027671
NP_001274742; NP_001274743; NP_001308702; NP_001308704; NP_001308705;
	NP_001308706; NP_001308707; NP_061840; NP_001274742.1; NP_061840.1; NP_001308702.1
	NP_001277319; NP_001277321; NP_001277322; NP_081947
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.

The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.