SOAT1

SOAT1
Identifiers
Aliases	SOAT1, ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT, sterol O-acyltransferase 1
External IDs	OMIM: 102642; MGI: 104665; HomoloGene: 2333; GeneCards: SOAT1; OMA:SOAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	179,358,680 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	156,301,901 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; skin of thigh; ; parotid gland; ; bronchial epithelial cell; ; endothelial cell; ; visceral pleura; ; monocyte; ; islet of Langerhans; ; ventricular zone;
	Top expressed in
	cumulus cell; ; lacrimal gland; ; parotid gland; ; ovary; ; medullary collecting duct; ; stroma of bone marrow; ; lip; ; decidua; ; adrenal gland; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; fatty-acyl-CoA binding; sterol O-acyltransferase activity; O-acyltransferase activity; cholesterol binding; protein binding; acyltransferase activity; cholesterol O-acyltransferase activity;
Cellular component	integral component of membrane; membrane; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	steroid metabolic process; macrophage derived foam cell differentiation; lipid metabolism; cholesterol metabolic process; cholesterol esterification; cholesterol storage; cholesterol efflux; positive regulation of amyloid precursor protein biosynthetic process; very-low-density lipoprotein particle assembly; cholesterol homeostasis; low-density lipoprotein particle clearance; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	6646
	20652
	ENSG00000057252
	ENSMUSG00000026600
	P35610
	Q61263
	NM_001252511; NM_001252512; NM_003101
	NM_009230
	NP_001239440; NP_001239441; NP_003092
	NP_033256
	Wikidata
View/Edit Human	View/Edit Mouse

Sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene.