SOBP

SOBP
Identifiers
Aliases	SOBP, JXC1, MRAMS, Sobp, sine oculis binding protein homolog
External IDs	OMIM: 613667; MGI: 1924427; HomoloGene: 41216; GeneCards: SOBP; OMA:SOBP - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	107,661,306 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	43,050,526 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; Brodmann area 23; ; tibia; ; entorhinal cortex; ; Brodmann area 46; ; cerebellar vermis; ; buccal mucosa cell; ; orbitofrontal cortex; ; postcentral gyrus;
	Top expressed in
	Rostral migratory stream; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; muscle of thigh; ; magnocellular part of medial dorsal nucleus; ; internal pyramidal layer of neocortex; ; facial motor nucleus; ; vestibular membrane of cochlear duct; ; skeletal muscle tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; SUMO polymer binding;
Cellular component	nucleus;
Biological process	cochlea development; hearing; inner ear morphogenesis; cognition; locomotory behavior;
	Sources:Amigo / QuickGO
Orthologs
	55084
	109205
	ENSG00000112320
	ENSMUSG00000038248
	A7XYQ1
	Q0P5V2
	NM_018013
	NM_175407
	NP_060483
	NP_780616
	Wikidata
View/Edit Human	View/Edit Mouse

Sine oculis-binding protein homolog (SOBP) also known as Jackson circler protein 1 (JXC1) is a protein that in humans is encoded by the SOBP gene. The first SOBP gene was identified in Drosophila melanogaster in a yeast two-hybrid screen that used the SIX domain of the Sine oculis protein as bait. In most genomes, which harbor SOBP, the gene is present as a single copy.