SOCS4

SOCS4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IZV
Identifiers
Aliases	SOCS4, SOCS7, suppressor of cytokine signaling 4
External IDs	OMIM: 616337; MGI: 1914546; HomoloGene: 15442; GeneCards: SOCS4; OMA:SOCS4 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	55,049,489 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	47,533,559 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; tibia; ; visceral pleura; ; parietal pleura; ; tail of epididymis; ; germinal epithelium; ; mucosa of ileum; ; mucosa of paranasal sinus; ; cardiac muscle tissue of right atrium; ; tibialis anterior muscle;
	Top expressed in
	medial ganglionic eminence; ; conjunctival fornix; ; vestibular membrane of cochlear duct; ; epithelium of small intestine; ; carotid body; ; atrioventricular valve; ; lymph node; ; trigeminal ganglion; ; lumbar spinal ganglion; ; hair follicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein kinase inhibitor activity; protein binding;
Cellular component	cytoplasm; intracellular anatomical structure;
Biological process	negative regulation of epidermal growth factor-activated receptor activity; regulation of growth; negative regulation of signal transduction; intracellular signal transduction; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; cytokine-mediated signaling pathway; negative regulation of receptor signaling pathway via JAK-STAT;
	Sources:Amigo / QuickGO
Orthologs
	122809
	67296
	ENSG00000180008
	ENSMUSG00000048379
	Q8WXH5
	Q91ZA6
	NM_080867; NM_199421
	NM_080843
	NP_543143; NP_955453
	NP_543119
	Wikidata
View/Edit Human	View/Edit Mouse

Suppressor of cytokine signaling 4 is a protein that in humans is encoded by the SOCS4 gene.