SOX11

SOX11
Identifiers
Aliases	SOX11, MRD27, SRY-box 11, CSS9, SRY-box transcription factor 11
External IDs	OMIM: 600898; MGI: 98359; HomoloGene: 37733; GeneCards: SOX11; OMA:SOX11 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	5,701,385 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	27,392,573 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; buccal mucosa cell; ; cartilage tissue; ; optic nerve; ; retinal pigment epithelium; ; internal globus pallidus; ; nucleus accumbens; ; Hypothalamus; ; Medulla Oblongata;
	Top expressed in
	Rostral migratory stream; ; medial ganglionic eminence; ; abdominal wall; ; maxillary prominence; ; genital tubercle; ; human fetus; ; mandibular prominence; ; fossa; ; otic vesicle; ; trigeminal ganglion;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription coactivator activity; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; translation factor activity, RNA binding; transcription cis-regulatory region binding; cis-regulatory region sequence-specific DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	cytoplasm; nucleus;
Biological process	embryonic skeletal system morphogenesis; skeletal system development; noradrenergic neuron differentiation; positive regulation of lens epithelial cell proliferation; cell differentiation; cardiac ventricle formation; glial cell development; regulation of transcription, DNA-templated; limb bud formation; lung morphogenesis; sympathetic nervous system development; neural crest cell development; kidney development; negative regulation of glial cell proliferation; soft palate development; ventricular septum morphogenesis; cornea development in camera-type eye; outflow tract morphogenesis; positive regulation of ossification; negative regulation of transcription by RNA polymerase II; negative regulation of cell death; transcription by RNA polymerase II; eyelid development in camera-type eye; negative regulation of gene expression; negative regulation of lymphocyte proliferation; somite development; transcription, DNA-templated; neuroepithelial cell differentiation; regulation of transforming growth factor beta receptor signaling pathway; nervous system development; positive regulation of transcription, DNA-templated; positive regulation of hippo signaling; positive regulation of neurogenesis; multicellular organism development; positive regulation of gene expression; positive regulation of osteoblast differentiation; lens morphogenesis in camera-type eye; negative regulation of transcription regulatory region DNA binding; hard palate development; positive regulation of neuron differentiation; neuron differentiation; positive regulation of cell population proliferation; spinal cord development; positive regulation of BMP signaling pathway; glial cell proliferation; skeletal muscle cell differentiation; embryonic digestive tract morphogenesis; oligodendrocyte development; cell population proliferation; positive regulation of stem cell proliferation; neural tube formation; positive regulation of hormone secretion; positive regulation of transcription by RNA polymerase II; closure of optic fissure; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	6664
	20666
	ENSG00000176887
	ENSMUSG00000063632
	P35716
	Q7M6Y2
	NM_003108
	NM_009234
	NP_003099
	NP_033260
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.