SOX17

SOX17
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YUL, 4A3N
Identifiers
Aliases	SOX17, VUR3, SRY-box 17, SRY-box transcription factor 17
External IDs	OMIM: 610928; MGI: 107543; HomoloGene: 7948; GeneCards: SOX17; OMA:SOX17 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	54,460,892 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	4,567,577 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; pericardium; ; endometrium; ; right uterine tube; ; vena cava; ; gonad; ; left uterine tube; ; tibial nerve; ; subcutaneous adipose tissue; ; muscle of thigh;
	Top expressed in
	left lung lobe; ; gastrula; ; external carotid artery; ; primitive streak; ; internal carotid artery; ; right lung; ; right lung lobe; ; uterus; ; carotid body; ; substantia nigra;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; beta-catenin binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription coactivator activity; transcription factor binding; protein binding; protein heterodimerization activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; nucleoplasm; nucleus;
Biological process	renal system development; endoderm development; regulation of embryonic development; regulation of transcription, DNA-templated; positive regulation of protein catabolic process; stem cell fate specification; positive regulation of skeletal muscle tissue development; embryonic foregut morphogenesis; embryonic organ development; endodermal digestive tract morphogenesis; negative regulation of mesodermal cell fate specification; inner cell mass cellular morphogenesis; negative regulation of Wnt signaling pathway; protein stabilization; endocardium formation; outflow tract morphogenesis; signal transduction involved in regulation of gene expression; endodermal cell fate determination; mRNA transcription by RNA polymerase II; regulation of mesodermal cell fate specification; negative regulation of transcription by RNA polymerase II; Wnt signaling pathway; endocardial cell differentiation; regulation of cardiac cell fate specification; transcription, DNA-templated; stem cell differentiation; embryonic heart tube development; vasculogenesis; positive regulation of transcription, DNA-templated; heart looping; cardiac cell fate determination; common bile duct development; negative regulation of Wnt signaling pathway involved in heart development; rostrocaudal neural tube patterning; positive regulation of gene expression; cardiogenic plate morphogenesis; heart formation; embryonic heart tube morphogenesis; negative regulation of cell growth; protein destabilization; angiogenesis; spermatogenesis; positive regulation of cell differentiation; regulation of stem cell division; gastrulation; gall bladder development; canonical Wnt signaling pathway; regulation of cell differentiation; cell migration involved in gastrulation; endoderm formation; regulation of stem cell proliferation; negative regulation of canonical Wnt signaling pathway; positive regulation of transcription by RNA polymerase II; cellular response to leukemia inhibitory factor; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	64321
	20671
	ENSG00000164736
	ENSMUSG00000025902
	Q9H6I2
	Q61473
	NM_022454
	NM_001289464; NM_001289465; NM_001289466; NM_001289467; NM_011441
	NP_071899
	NP_001276393; NP_001276394; NP_001276395; NP_001276396; NP_035571
	Wikidata
View/Edit Human	View/Edit Mouse

SRY-box 17 is a protein that in humans is encoded by the SOX17 gene.