SOX18

SOX18
Identifiers
Aliases	SOX18, HLTS, HLTRS, SRY-box 18, SRY-box transcription factor 18
External IDs	OMIM: 601618; MGI: 103559; HomoloGene: 7546; GeneCards: SOX18; OMA:SOX18 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	64,049,639 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	181,313,433 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right lung; ; left uterine tube; ; right auricle of heart; ; right lobe of thyroid gland; ; left ventricle; ; right coronary artery; ; gastric mucosa; ; body of uterus; ; left coronary artery;
	Top expressed in
	interventricular septum; ; glomerular capillary; ; right lung; ; endothelial cell of lymphatic vessel; ; left lung; ; right lung lobe; ; external carotid artery; ; left lung lobe; ; lactiferous gland; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	hair follicle development; establishment of endothelial barrier; hair cycle process; regulation of transcription, DNA-templated; stem cell fate specification; lymphangiogenesis; blood vessel endothelial cell migration; lymphatic endothelial cell differentiation; endocardium formation; outflow tract morphogenesis; mRNA transcription by RNA polymerase II; in utero embryonic development; negative regulation of transcription by RNA polymerase II; cell maturation; endocardial cell differentiation; lymph vessel development; transcription, DNA-templated; embryonic heart tube development; vasculogenesis; positive regulation of transcription, DNA-templated; heart looping; heart development; vasculature development; blood vessel development; angiogenesis; negative regulation of transcription, DNA-templated; regulation of stem cell proliferation; positive regulation of transcription by RNA polymerase II; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	54345
	20672
	ENSG00000203883
	ENSMUSG00000046470
	P35713
	P43680
	NM_018419
	NM_009236
	NP_060889
	NP_033262
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor SOX-18 is a protein that in humans is encoded by the SOX18 gene.