SOX6

SOX6
Identifiers
Aliases	SOX6, HSSOXD, SRY-box 6, SRY-box transcription factor 6, TOLCAS
External IDs	OMIM: 607257; MGI: 98368; HomoloGene: 22631; GeneCards: SOX6; OMA:SOX6 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	16,739,591 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	116,038,796 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; tibia; ; deltoid muscle; ; sperm; ; sural nerve; ; mucosa of ileum; ; tibialis anterior muscle; ; pancreatic ductal cell; ; ventricular zone; ; jejunal mucosa;
	Top expressed in
	triceps brachii muscle; ; vastus lateralis muscle; ; fetal liver hematopoietic progenitor cell; ; temporal muscle; ; sternocleidomastoid muscle; ; muscle of thigh; ; knee joint; ; ventricular zone; ; medial ganglionic eminence; ; medial head of gastrocnemius muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; protein binding; protein heterodimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus;
Biological process	cellular response to transforming growth factor beta stimulus; cell fate commitment; regulation of transcription, DNA-templated; cardiac muscle cell differentiation; muscle organ development; oligodendrocyte differentiation; in utero embryonic development; negative regulation of transcription by RNA polymerase II; post-embryonic development; transcription, DNA-templated; positive regulation of mesenchymal stem cell differentiation; multicellular organism development; positive regulation of transcription, DNA-templated; oligodendrocyte cell fate specification; muscle cell differentiation; cartilage development; astrocyte differentiation; positive regulation of cartilage development; positive regulation of chondrocyte differentiation; cell morphogenesis; regulation of gene expression; erythrocyte differentiation; negative regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; erythrocyte development; negative regulation of cardiac muscle cell differentiation; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	55553
	20679
	ENSG00000110693
	ENSMUSG00000051910
	P35712
	P40645
NM_033326; NM_001145811; NM_001145819; NM_017508; NM_001367872;
	NM_001367873
NM_001025559; NM_001025560; NM_001277326; NM_001277327; NM_001277328;
	NM_011445
NP_001139283; NP_001139291; NP_059978; NP_201583; NP_001354801;
	NP_001354802
NP_001020730; NP_001020731; NP_001264255; NP_001264256; NP_001264257;
	NP_035575
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor SOX-6 is a protein that in humans is encoded by the SOX6 gene.