Sperm-associated antigen 5

SPAG5
Identifiers
Aliases	SPAG5, DEEPEST, MAP126, hMAP126, Sperm associated antigen 5
External IDs	OMIM: 615562; MGI: 1927470; HomoloGene: 4718; GeneCards: SPAG5; OMA:SPAG5 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	28,599,025 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	78,213,283 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; ventricular zone; ; gonad; ; ganglionic eminence; ; mucosa of transverse colon; ; testicle; ; right lobe of liver; ; right lobe of thyroid gland; ; human kidney;
	Top expressed in
	epithelium of lens; ; spermatocyte; ; ventricular zone; ; spermatid; ; tail of embryo; ; lumbar subsegment of spinal cord; ; seminiferous tubule; ; epiblast; ; genital tubercle; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; microtubule binding;
Cellular component	spindle; mitotic spindle; chromosome; microtubule organizing center; centriolar satellite; spindle pole; chromosome, centromeric region; microtubule plus-end; midbody; microtubule; kinetochore; cytoskeleton; cytoplasm; mitotic spindle pole; spindle microtubule;
Biological process	mitotic sister chromatid segregation; cell cycle; spindle organization; cell division; protein localization to centrosome; chromosome segregation; regulation of attachment of spindle microtubules to kinetochore; positive regulation of intracellular transport; regulation of metaphase plate congression; positive regulation of spindle assembly; establishment of spindle orientation;
	Sources:Amigo / QuickGO
Orthologs
	10615
	54141
	ENSG00000076382
	ENSMUSG00000002055
	Q96R06
	Q7TME2
	NM_006461
	NM_017407
	NP_006452
	NP_059103
	Wikidata
View/Edit Human	View/Edit Mouse

Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene.

This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles.