Sperm-associated antigen 9

SPAG9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2W83
Identifiers
Aliases	SPAG9, CT89, HLC-6, HLC4, JIP-4, JIP4, JLP, PHET, PIG6, HLC6, sperm associated antigen 9
External IDs	OMIM: 605430; MGI: 1918084; HomoloGene: 2954; GeneCards: SPAG9; OMA:SPAG9 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	51,120,868 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	94,016,911 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ventricular zone; ; sural nerve; ; ganglionic eminence; ; corpus callosum; ; internal globus pallidus; ; inferior ganglion of vagus nerve; ; endothelial cell; ; cartilage tissue; ; subthalamic nucleus;
	Top expressed in
	otolith organ; ; utricle; ; superior cervical ganglion; ; sciatic nerve; ; trigeminal ganglion; ; substantia nigra; ; mammillary body; ; superior colliculus; ; cerebellar vermis; ; lobe of cerebellum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	JUN kinase binding; MAP-kinase scaffold activity; mitogen-activated protein kinase p38 binding; protein binding; kinesin binding; signaling receptor complex adaptor activity;
Cellular component	integral component of membrane; microtubule organizing center; acrosomal vesicle; perinuclear region of cytoplasm; extracellular exosome; cytoplasmic vesicle; cytoplasm; cytosol; lysosomal membrane;
Biological process	positive regulation of muscle cell differentiation; positive regulation of cell migration; retrograde transport, endosome to Golgi; positive regulation of neuron differentiation; spermatogenesis; negative regulation of protein homodimerization activity; striated muscle cell differentiation; protein homooligomerization; positive regulation of MAPK cascade; vesicle-mediated transport; lysosome localization;
	Sources:Amigo / QuickGO
Orthologs
	9043
	70834
	ENSG00000008294
	ENSMUSG00000020859
	O60271
	Q58A65
	NM_001130527; NM_001130528; NM_001251971; NM_003971; NM_172345
NM_001025428; NM_001025429; NM_001025430; NM_001199203; NM_001199204;
	NM_001199205; NM_027569; NM_001363157
	NP_001123999; NP_001124000; NP_001238900; NP_003962
NP_001020599; NP_001020600; NP_001020601; NP_001186132; NP_001186133;
	NP_001186134; NP_081845; NP_001350086
	Wikidata
View/Edit Human	View/Edit Mouse

C-jun-amino-terminal kinase-interacting protein 4 is a scaffold protein that in humans is encoded by the SPAG9 gene.