SPINK2

SPINK2
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2JXD
Identifiers
Aliases	SPINK2, HUSI-II, serine peptidase inhibitor, Kazal type 2, SPGF29, serine peptidase inhibitor Kazal type 2
External IDs	OMIM: 605753; HomoloGene: 77717; GeneCards: SPINK2; OMA:SPINK2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	56,821,742 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; tail of epididymis; ; seminal vesicula; ; right testis; ; left testis; ; male germ cell; ; sperm; ; caput epididymis; ; gonad; ; testicle;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity;
Cellular component	extracellular region; acrosomal vesicle; extracellular space; cytoplasmic vesicle;
Biological process	regulation of acrosome reaction; negative regulation of peptidase activity; negative regulation of serine-type endopeptidase activity; spermatogenesis; acrosome assembly; spermatid development;
	Sources:Amigo / QuickGO
Orthologs
	6691
	n/a
	ENSG00000128040
	n/a
	P20155
	n/a
NM_001271718; NM_001271719; NM_001271720; NM_001271721; NM_001271722;
	NM_021114
	n/a
NP_001258647; NP_001258648; NP_001258649; NP_001258650; NP_001258651;
	NP_066937
	n/a
	Wikidata
View/Edit Human

Serine protease inhibitor Kazal-type 2 also known as acrosin-trypsin inhibitor is a protein that in humans is encoded by the SPINK2 gene.