SPRY4

SPRY4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BUN
Identifiers
Aliases	SPRY4, HH17, sprouty RTK signaling antagonist 4
External IDs	OMIM: 607984; MGI: 1345144; HomoloGene: 8042; GeneCards: SPRY4; OMA:SPRY4 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	142,326,455 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	38,734,468 bp
RNA expression pattern
	Top expressed in
	left coronary artery; ; right lung; ; ascending aorta; ; upper lobe of left lung; ; Descending thoracic aorta; ; cartilage tissue; ; right coronary artery; ; lower lobe of lung; ; tibial arteries; ; left adrenal gland;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; tail of embryo; ; zygote; ; left lung lobe; ; lumbar spinal ganglion; ; entorhinal cortex; ; perirhinal cortex; ; Ileal epithelium; ; nasolacrimal duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	ruffle membrane; plasma membrane; cell projection; membrane; focal adhesion; cytoplasm; cytosol;
Biological process	multicellular organism development; negative regulation of ERK1 and ERK2 cascade; regulation of signal transduction; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of MAP kinase activity; negative regulation of Ras protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	81848
	24066
	ENSG00000187678
	ENSMUSG00000024427
	Q9C004
	Q9WTP2
	NM_001127496; NM_001293289; NM_001293290; NM_030964
	NM_011898
	NP_001120968; NP_001280218; NP_001280219; NP_112226
	NP_036028
	Wikidata
View/Edit Human	View/Edit Mouse

Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene.