SPTBN2

SPTBN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WJM, 1WYQ
Identifiers
Aliases	SPTBN2, GTRAP41, SCA5, SCAR14, spectrin beta, non-erythrocytic 2
External IDs	OMIM: 604985; MGI: 1313261; HomoloGene: 48482; GeneCards: SPTBN2; OMA:SPTBN2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	66,744,670 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	4,802,388 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; skin of leg; ; skin of abdomen; ; ganglionic eminence; ; prefrontal cortex; ; right testis; ; left testis; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	perirhinal cortex; ; CA3 field; ; entorhinal cortex; ; superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; Region I of hippocampus proper; ; primary motor cortex; ; cerebellar cortex; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; phospholipid binding; structural constituent of cytoskeleton; cadherin binding; structural constituent of synapse;
Cellular component	cell junction; soma; cell cortex; apical plasma membrane; cytoskeleton; spectrin; extracellular space; cytoplasm; cytosol; parallel fiber to Purkinje cell synapse; presynapse; glutamatergic synapse; postsynaptic spectrin-associated cytoskeleton;
Biological process	antigen processing and presentation of exogenous peptide antigen via MHC class II; multicellular organism growth; MAPK cascade; axon guidance; cerebellar Purkinje cell layer morphogenesis; endoplasmic reticulum to Golgi vesicle-mediated transport; adult behavior; actin filament capping; synapse assembly; vesicle-mediated transport; cytoskeleton organization; regulation of molecular function; postsynapse organization;
	Sources:Amigo / QuickGO
Orthologs
	6712
	20743
	ENSG00000173898
	ENSMUSG00000067889
	O15020
	Q68FG2
	NM_006946
	NM_021287
	NP_008877
	NP_067262
	Wikidata
View/Edit Human	View/Edit Mouse

Spectrin beta chain, brain 2 is a protein that in humans is encoded by the SPTBN2 gene.