SRI (gene)

SRI
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1JUO, 2JC2, 4U8D, 4UPG, 4USL
Identifiers
Aliases	SRI, CP-22, CP22, SCN, V19, sorcin
External IDs	OMIM: 182520; MGI: 98419; HomoloGene: 37736; GeneCards: SRI; OMA:SRI - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	88,226,993 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	8,119,379 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of sigmoid colon; ; rectum; ; bronchial epithelial cell; ; mucosa of ileum; ; ventricular zone; ; oocyte; ; secondary oocyte; ; right uterine tube; ; nucleus accumbens;
	Top expressed in
	granulocyte; ; left colon; ; mucous cell of stomach; ; duodenum; ; pyloric antrum; ; Paneth cell; ; endocardial cushion; ; epithelium of stomach; ; decidua; ; right kidney;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; transmembrane transporter binding; calcium channel regulator activity; metal ion binding; calcium-dependent cysteine-type endopeptidase activity; protease binding; protein binding; protein heterodimerization activity; identical protein binding; signaling receptor binding;
Cellular component	axon terminus; dendritic spine neck; vesicle; cytosol; endoplasmic reticulum membrane; membrane; T-tubule; plasma membrane; intracellular anatomical structure; sarcoplasmic reticulum; nucleoplasm; smooth endoplasmic reticulum; axon; chromaffin granule membrane; Z discdkac; mitochondrion; sarcoplasmic reticulum membrane; extracellular exosome; cytoplasm;
Biological process	regulation of calcium ion transport; regulation of heart contraction; cytoplasmic sequestering of transcription factor; muscle organ development; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of heart rate; proteolysis; negative regulation of ryanodine-sensitive calcium-release channel activity; regulation of cardiac muscle cell contraction; heart development; intracellular sequestering of iron ion; regulation of striated muscle contraction; negative regulation of transcription regulatory region DNA binding; regulation of high voltage-gated calcium channel activity; action potential; positive regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of cell communication by electrical coupling; regulation of cell communication by electrical coupling involved in cardiac conduction; regulation of relaxation of muscle; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; calcium ion transport; signal transduction; negative regulation of cardiac muscle contraction; transport;
	Sources:Amigo / QuickGO
Orthologs
	6717
	109552
	ENSG00000075142
	ENSMUSG00000003161
	P30626
	Q6P069
	NM_001256891; NM_001256892; NM_003130; NM_198901
	NM_001080974; NM_025618
	NP_001243820; NP_001243821; NP_003121; NP_944490
	NP_001074443; NP_079894
	Wikidata
View/Edit Human	View/Edit Mouse

Sorcin is a protein that in humans is encoded by the SRI gene.