SSX2IP

SSX2IP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1T2M, 1XZ9, 2AIN, 2EXG
Identifiers
Aliases	SSX2IP, ADIP, synovial sarcoma, X breakpoint 2 interacting protein, SSX family member 2 interacting protein, hMsd1
External IDs	OMIM: 608690; MGI: 2139150; HomoloGene: 8522; GeneCards: SSX2IP; OMA:SSX2IP - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	84,690,803 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	146,145,899 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; middle temporal gyrus; ; sperm; ; Brodmann area 23; ; jejunal mucosa; ; Brodmann area 46; ; endothelial cell; ; duodenum; ; secondary oocyte;
	Top expressed in
	Ileal epithelium; ; seminiferous tubule; ; spermatid; ; olfactory epithelium; ; lens; ; spermatocyte; ; fetal liver hematopoietic progenitor cell; ; CA3 field; ; retinal pigment epithelium; ; entorhinal cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein domain specific binding;
Cellular component	cytoplasm; microtubule organizing center; adherens junction; cell junction; cell projection; cytoskeleton; cell leading edge; nucleus; ciliary basal body; centriolar satellite; protein-containing complex;
Biological process	regulation of cell motility; intraciliary transport involved in cilium assembly; regulation of Rac protein signal transduction; cell adhesion; cell projection organization; cilium assembly; centrosome cycle;
	Sources:Amigo / QuickGO
Orthologs
	117178
	99167
	ENSG00000117155
	ENSMUSG00000036825
	Q9Y2D8
	Q8VC66
	NM_001166293; NM_001166294; NM_001166295; NM_001166417; NM_014021
	NM_001253768; NM_001253769; NM_001253770; NM_138744; NM_001355661
	NP_001159765; NP_001159766; NP_001159767; NP_001159889; NP_054740
	NP_001240697; NP_001240698; NP_001240699; NP_620083; NP_001342590
	Wikidata
View/Edit Human	View/Edit Mouse

Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene. It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation. The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.