STAT5A

STAT5A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Y1U
Identifiers
Aliases	STAT5A, MGF, STAT5, signal transducer and activator of transcription 5A
External IDs	OMIM: 601511; MGI: 103036; HomoloGene: 20680; GeneCards: STAT5A; OMA:STAT5A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,311,943 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,775,995 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; left adrenal cortex; ; right adrenal cortex; ; subcutaneous adipose tissue; ; tendon of biceps brachii; ; blood; ; gastric mucosa; ; appendix; ; lymph node;
	Top expressed in
	lactiferous gland; ; seminal vesicula; ; Ileal epithelium; ; thymus; ; brown adipose tissue; ; cumulus cell; ; perirhinal cortex; ; parotid gland; ; granulocyte; ; choroid plexus of fourth ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA-binding transcription factor activity; protein tyrosine kinase activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	creatinine metabolic process; positive regulation of endothelial cell proliferation; receptor signaling pathway via JAK-STAT; transcription, DNA-templated; signal transduction; valine metabolic process; creatine metabolic process; regulation of transcription by RNA polymerase II; positive regulation of blood vessel endothelial cell migration; fatty acid metabolic process; taurine metabolic process; succinate metabolic process; regulation of multicellular organism growth; citrate metabolic process; oxaloacetate metabolic process; regulation of transcription, DNA-templated; allantoin metabolic process; isoleucine metabolic process; lactation; 2-oxoglutarate metabolic process; peptidyl-tyrosine phosphorylation; interleukin-7-mediated signaling pathway; growth hormone receptor signaling pathway via JAK-STAT; interleukin-15-mediated signaling pathway; cytokine-mediated signaling pathway; interleukin-2-mediated signaling pathway; interleukin-9-mediated signaling pathway; reelin-mediated signaling pathway; defense response; regulation of cell population proliferation; response to peptide hormone; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6776
	20850
	ENSG00000126561
	ENSMUSG00000004043
	P42229
	P42230
	NM_001288718; NM_001288719; NM_001288720; NM_003152
	NM_001164062; NM_011488; NM_001362680
	NP_001275647; NP_001275648; NP_001275649; NP_003143
	NP_001157534; NP_035618; NP_001349609
	Wikidata
View/Edit Human	View/Edit Mouse

Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. STAT5A orthologs have been identified in several placentals for which complete genome data are available.