STK4

STK4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3COM, 4NR2, 4OH8, 2JO8
Identifiers
Aliases	STK4, KRS2, MST1, TIIAC, YSK3, serine/threonine kinase 4
External IDs	OMIM: 604965; MGI: 1929004; HomoloGene: 55965; GeneCards: STK4; OMA:STK4 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	45,080,021 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	163,997,444 bp
RNA expression pattern
	Top expressed in
	epithelium of colon; ; buccal mucosa cell; ; blood; ; monocyte; ; superficial temporal artery; ; trabecular bone; ; pylorus; ; tonsil; ; lymph node; ; saphenous vein;
	Top expressed in
	mesenteric lymph nodes; ; blood; ; right lung lobe; ; fossa; ; spleen; ; condyle; ; left lung lobe; ; thymus; ; stroma of bone marrow; ; Gonadal ridge;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; protein dimerization activity; protein homodimerization activity; transcription factor binding; protein serine/threonine kinase activator activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; protein binding; identical protein binding; ATP binding; magnesium ion binding;
Cellular component	cytoplasm; nucleus; nucleoplasm; cytosol; nuclear body; protein-containing complex;
Biological process	regulation of cell differentiation involved in embryonic placenta development; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of protein phosphorylation; intracellular signal transduction; phosphorylation; protein stabilization; hippo signaling; keratinocyte differentiation; positive regulation of peptidyl-serine phosphorylation; endocardium development; protein phosphorylation; primitive hemopoiesis; central nervous system development; peptidyl-serine phosphorylation; cell morphogenesis; positive regulation of apoptotic process; branching involved in blood vessel morphogenesis; protein autophosphorylation; positive regulation of protein binding; cell differentiation involved in embryonic placenta development; positive regulation of fat cell differentiation; negative regulation of organ growth; neural tube formation; negative regulation of canonical Wnt signaling pathway; signal transduction; negative regulation of cell population proliferation; hepatocyte apoptotic process; apoptotic process; positive regulation of protein serine/threonine kinase activity; regulation of mitotic cell cycle; stress-activated protein kinase signaling cascade; positive regulation of vascular associated smooth muscle cell apoptotic process; activation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	6789
	58231
	ENSG00000101109
	ENSMUSG00000018209
	Q13043
	Q9JI11
	NM_006282; NM_001352385
	NM_021420
	NP_006273; NP_001339314
	NP_067395
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene.