STOX1

STOX1
Identifiers
Aliases	STOX1, C10orf24, PEE4, storkhead box 1
External IDs	OMIM: 609397; MGI: 2684909; HomoloGene: 17649; GeneCards: STOX1; OMA:STOX1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	68,895,432 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	62,561,907 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; ventricular zone; ; Amygdala; ; gonad; ; mucosa of paranasal sinus; ; endothelial cell; ; cingulate gyrus; ; anterior cingulate cortex; ; nucleus accumbens; ; olfactory zone of nasal mucosa;
	Top expressed in
	spermatocyte; ; otolith organ; ; morula; ; utricle; ; islet of Langerhans; ; vestibular sensory epithelium; ; olfactory epithelium; ; retinal pigment epithelium; ; embryo; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding;
Cellular component	cytoplasm; centrosome; nucleoplasm; microtubule organizing center; cell cortex; cytoskeleton; nucleus; fibrillar center; nucleolus; cytosol;
Biological process	positive regulation of protein kinase B signaling; regulation of transcription, DNA-templated; regulation of mitochondrion organization; regulation of mitochondrial DNA metabolic process; positive regulation of epithelial cell proliferation; negative regulation of gene expression; transcription, DNA-templated; positive regulation of peptidyl-serine phosphorylation; positive regulation of cyclin-dependent protein kinase activity; cell division; regulation of mitochondrial membrane potential; positive regulation of gene expression; positive regulation of cell cycle; positive regulation of peptidyl-threonine phosphorylation; positive regulation of cell population proliferation; regulation of transcription from RNA polymerase II promoter in response to hypoxia; regulation of response to oxidative stress; regulation of gene expression; inner ear development; positive regulation of G2/M transition of mitotic cell cycle; cell cycle; cellular response to nitrosative stress; positive regulation of otic vesicle morphogenesis; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	219736
	216021
	ENSG00000165730
	ENSMUSG00000036923
	Q6ZVD7
	B2RQL2
	NM_001130159; NM_001130160; NM_001130161; NM_001130162; NM_152709
	NM_001033260; NM_001364705
	NP_001123631; NP_001123632; NP_001123633; NP_689922
	NP_001028432; NP_001351634
	Wikidata
View/Edit Human	View/Edit Mouse

Storkhead box 1 is a protein in humans that is encoded by the STOX1 gene.

The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].