STX4

STX4
Identifiers
Aliases	STX4, STX4A, p35-2, syntaxin 4
External IDs	OMIM: 186591; MGI: 893577; HomoloGene: 105435; GeneCards: STX4; OMA:STX4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,042,975 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,448,191 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; granulocyte; ; skin of leg; ; skin of abdomen; ; upper lobe of left lung; ; canal of the cervix; ; right lung; ; left uterine tube; ; sural nerve; ; left adrenal cortex;
	Top expressed in
	Ileal epithelium; ; motor neuron; ; lip; ; yolk sac; ; muscle of thigh; ; granulocyte; ; fossa; ; superior frontal gyrus; ; neural layer of retina; ; condyle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SNAP receptor activity; protein binding; sphingomyelin phosphodiesterase activator activity; SNARE binding;
Cellular component	cytoplasm; integral component of membrane; cytosol; endosome; membrane; synaptic vesicle; plasma membrane; myelin sheath adaxonal region; dendritic spine; synapse; intracellular anatomical structure; cell surface; vacuole; trans-Golgi network; basolateral plasma membrane; somatodendritic compartment; specific granule; lateral loop; perinuclear region of cytoplasm; storage vacuole; extracellular exosome; lamellipodium; SNARE complex; extracellular space; phagocytic vesicle membrane; endomembrane system; presynaptic membrane; phagocytic vesicle; presynaptic active zone membrane; postsynapse; glutamatergic synapse;
Biological process	positive regulation of eosinophil degranulation; positive regulation of cell migration; organelle fusion; synaptic vesicle fusion to presynaptic active zone membrane; response to hydroperoxide; positive regulation of catalytic activity; post-Golgi vesicle-mediated transport; regulation of exocytosis; vesicle docking; positive regulation of protein localization to plasma membrane; positive regulation of chemotaxis; positive regulation of cell population proliferation; positive regulation of protein localization to cell surface; regulation of extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of insulin secretion involved in cellular response to glucose stimulus; intracellular protein transport; neurotransmitter transport; vesicle-mediated transport; SNARE complex assembly; positive regulation of cell adhesion; long-term potentiation; vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; transport; exocytosis; vesicle fusion; cytokine-mediated signaling pathway; cellular response to interferon-gamma;
	Sources:Amigo / QuickGO
Orthologs
	6810
	20909
	ENSG00000103496
	ENSMUSG00000030805
	Q12846
	P70452
	NM_001272095; NM_001272096; NM_004604
	NM_009294
	NP_001259024; NP_001259025; NP_004595
	NP_033320
	Wikidata
View/Edit Human	View/Edit Mouse

Syntaxin-4 is a protein that in humans is encoded by the STX4 gene.