STXBP5

STXBP5
Identifiers
Aliases	STXBP5, Tomosyn, LGL3, LLGL3, Nbla04300, syntaxin binding protein 5
External IDs	OMIM: 604586; MGI: 1926058; HomoloGene: 16402; GeneCards: STXBP5; OMA:STXBP5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	147,390,476 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	9,901,079 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; Achilles tendon; ; cerebellar hemisphere; ; endothelial cell; ; Brodmann area 9; ; sperm; ; right hemisphere of cerebellum; ; superior frontal gyrus; ; primary visual cortex; ; Brodmann area 46;
	Top expressed in
	zygote; ; secondary oocyte; ; granulocyte; ; mammillary body; ; paraventricular nucleus of hypothalamus; ; supraoptic nucleus; ; inferior colliculi; ; neural layer of retina; ; habenula; ; dentate gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase activator activity; syntaxin-1 binding; syntaxin binding; myosin II binding;
Cellular component	integral component of membrane; acetylcholine-gated channel complex; membrane; synaptic vesicle; plasma membrane; synapse; cell junction; cytoplasmic vesicle membrane; cytoplasmic vesicle; cytosol; cytoplasm; neuromuscular junction; Schaffer collateral - CA1 synapse; extrinsic component of presynaptic membrane; presynaptic cytosol; SNARE complex;
Biological process	regulation of exocytosis; protein transport; positive regulation of exocytosis; vesicle-mediated transport; exocytosis; regulation of protein secretion; positive regulation of GTPase activity; synaptic vesicle cycle;
	Sources:Amigo / QuickGO
Orthologs
	134957
	78808
	ENSG00000164506
	ENSMUSG00000019790
	Q5T5C0
	Q8K400
	NM_001127715; NM_139244; NM_001394409
	NM_001081344; NM_030191
	NP_001121187; NP_640337
	NP_001074813; NP_001394992; NP_001394993; NP_001394994
	Wikidata
View/Edit Human	View/Edit Mouse

Syntaxin-binding protein 5 is a protein that in humans is encoded by the STXBP5 gene. It is also known as tomosyn, after 友, "friend" in Japanese, for its role as a binding protein.