SULF2

SULF2
Identifiers
Aliases	SULF2, HSULF-2, sulfatase 2
External IDs	OMIM: 610013; MGI: 1919293; HomoloGene: 10313; GeneCards: SULF2; OMA:SULF2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	47,786,616 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	165,997,583 bp
RNA expression pattern
	Top expressed in
	decidua; ; body of uterus; ; myometrium; ; left ovary; ; right ovary; ; ectocervix; ; left uterine tube; ; monocyte; ; tendon of biceps brachii; ; smooth muscle tissue;
	Top expressed in
	tail of embryo; ; calvaria; ; genital tubercle; ; fossa; ; umbilical cord; ; condyle; ; abdominal wall; ; decidua; ; endothelial cell of lymphatic vessel; ; transitional epithelium of urinary bladder;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; arylsulfatase activity; metal ion binding; catalytic activity; sulfuric ester hydrolase activity; hydrolase activity; N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding;
Cellular component	Golgi apparatus; plasma membrane; cell surface; endoplasmic reticulum; Golgi stack; extracellular space;
Biological process	glomerular basement membrane development; kidney development; positive regulation of canonical Wnt signaling pathway; chondrocyte development; embryonic skeletal system development; positive regulation of Wnt signaling pathway; negative regulation of fibroblast growth factor receptor signaling pathway; liver regeneration; cartilage development; glomerular filtration; response to wounding; regulation of hepatocyte proliferation; glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of vascular endothelial growth factor production; metabolism; esophagus smooth muscle contraction; innervation; bone development; heparan sulfate proteoglycan metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	55959
	72043
	ENSG00000196562
	ENSMUSG00000006800
	Q8IWU5
	Q8CFG0
	NM_001161841; NM_018837; NM_198596
	NM_001252578; NM_001252579; NM_028072; NM_001355619
	NP_001155313; NP_061325; NP_940998
	NP_001239507; NP_001239508; NP_082348; NP_001342548
	Wikidata
View/Edit Human	View/Edit Mouse

Extracellular sulfatase Sulf-2 is an enzyme that in humans is encoded by the SULF2 gene.