SUMO1

SUMO1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WJQ, 1A5R, 1TGZ, 1WYW, 1Y8R, 1Z5S, 2ASQ, 2BF8, 2G4D, 2IO2, 2IY0, 2IY1, 2KQS, 2LAS, 2MW5, 2PE6, 2UYZ, 2VRR, 3KYC, 3KYD, 3RZW, 3UIP, 4WJN, 4WJO, 4WJP, 5AEK, 2N1V, 2N1A
Identifiers
Aliases	SUMO1, DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1, small ubiquitin-like modifier 1, small ubiquitin like modifier 1
External IDs	OMIM: 601912; MGI: 1197010; HomoloGene: 2514; GeneCards: SUMO1; OMA:SUMO1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	202,238,608 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	59,709,993 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; monocyte; ; rectum; ; gallbladder; ; right adrenal cortex; ; olfactory zone of nasal mucosa; ; epithelium of colon; ; anterior cingulate cortex; ; left adrenal gland;
	Top expressed in
	morula; ; epiblast; ; neural tube; ; ventricular zone; ; ganglionic eminence; ; embryo; ; blastocyst; ; embryo; ; Mesencephalon; ; ovary;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transcription factor binding; potassium channel regulator activity; protein binding; protein tag; ubiquitin protein ligase binding; RNA binding; transcription corepressor binding; protein C-terminus binding; SUMO transferase activity; enzyme binding; protein-macromolecule adaptor activity; glucocorticoid receptor binding; small protein activating enzyme binding; ubiquitin-like protein ligase binding;
Cellular component	cytoplasm; PML body; nuclear speck; nuclear body; nuclear membrane; membrane; voltage-gated potassium channel complex; plasma membrane; synapse; nuclear pore; nucleoplasm; heterochromatin; XY body; dendrite; nucleolus; fibrillar center; nucleus; nuclear stress granule; SUMO activating enzyme complex; nuclear envelope; cytosol;
Biological process	roof of mouth development; regulation of transcription, DNA-templated; regulation of protein stability; positive regulation of protein-containing complex assembly; protein localization to nuclear pore; protein stabilization; negative regulation of action potential; negative regulation of DNA-binding transcription factor activity; regulation of protein localization; regulation of cardiac muscle cell contraction; global genome nucleotide-excision repair; PML body organization; regulation of interferon-gamma-mediated signaling pathway; viral process; negative regulation of transcription, DNA-templated; double-strand break repair via nonhomologous end joining; regulation of calcium ion transmembrane transport; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of delayed rectifier potassium channel activity; positive regulation of ATPase-coupled calcium transmembrane transporter activity; DNA repair; negative regulation of transcription by RNA polymerase II; cellular response to heat; cellular response to cadmium ion; protein sumoylation; negative regulation of DNA binding;
	Sources:Amigo / QuickGO
Orthologs
	7341
	22218
	ENSG00000116030
	ENSMUSG00000026021
	P63165
	P63166
	NM_003352; NM_001005781; NM_001005782
	NM_009460
NP_001005781; NP_001005782; NP_003343; NP_001358321; NP_001358322;
	NP_001358323
	NP_033486
	Wikidata
View/Edit Human	View/Edit Mouse

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.