SUZ12

SUZ12
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5IJ7, 5IJ8, 5HYN
Identifiers
Aliases	SUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit, polycomb repressive complex 2 subunit, IMMAS
External IDs	OMIM: 606245; MGI: 1261758; HomoloGene: 32256; GeneCards: SUZ12; OMA:SUZ12 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	32,001,038 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	79,924,949 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; mucosa of paranasal sinus; ; buccal mucosa cell; ; Epithelium of choroid plexus; ; pylorus; ; renal medulla; ; seminal vesicula; ; hair follicle; ; cartilage tissue; ; ventricular zone;
	Top expressed in
	medullary collecting duct; ; zygote; ; secondary oocyte; ; renal corpuscle; ; primary oocyte; ; atrioventricular valve; ; saccule; ; ventricular zone; ; tail of embryo; ; otic placode;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	histone methyltransferase activity; sequence-specific DNA binding; chromatin binding; metal ion binding; methylated histone binding; protein binding; RNA binding; RNA polymerase II core promoter sequence-specific DNA binding; chromatin DNA binding; promoter-specific chromatin binding; histone methyltransferase activity (H3-K27 specific); RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	sex chromatin; ESC/E(Z) complex; nucleoplasm; protein-DNA complex; nucleolus; nucleus; RSC-type complex; nuclear body;
Biological process	negative regulation of cell differentiation; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; negative regulation of gene expression, epigenetic; positive regulation of cell population proliferation; histone methylation; histone ubiquitination; regulation of transcription, DNA-templated; histone H3-K27 methylation; negative regulation of G0 to G1 transition; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	23512
	52615
	ENSG00000178691
	ENSMUSG00000017548
	Q15022
	Q80U70
	NM_015355; NM_001321207
	NM_001163018; NM_199196
	NP_001308136; NP_056170
	NP_001156490; NP_954666
	Wikidata
View/Edit Human	View/Edit Mouse

Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.