Synapsin 2

SYN2
Identifiers
Aliases	SYN2, SYNII, Synapsin 2, synapsin II
External IDs	OMIM: 600755; MGI: 103020; HomoloGene: 49348; GeneCards: SYN2; OMA:SYN2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	12,192,032 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	115,258,967 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; endothelial cell; ; Brodmann area 23; ; superior frontal gyrus; ; entorhinal cortex; ; postcentral gyrus; ; Pons; ; right frontal lobe; ; prefrontal cortex; ; dorsolateral prefrontal cortex;
	Top expressed in
	subiculum; ; dentate gyrus of hippocampal formation granule cell; ; anterior amygdaloid area; ; medial dorsal nucleus; ; olfactory tubercle; ; dorsomedial hypothalamic nucleus; ; ventromedial nucleus; ; piriform cortex; ; dorsal tegmental nucleus; ; pontine nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP binding;
Cellular component	cell junction; synapse; synaptic vesicle membrane; synaptic vesicle; plasma membrane; postsynaptic density; SNARE complex; myelin sheath; Schaffer collateral - CA1 synapse; glutamatergic synapse;
Biological process	neurotransmitter secretion; chemical synaptic transmission; synaptic vesicle clustering; synaptic vesicle cycle; calcium-ion regulated exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	6854
	20965
	ENSG00000157152
	ENSMUSG00000009394
	Q92777
	Q64332
	NM_003178; NM_133625
	NM_001111015; NM_013681; NM_001326560
	NP_003169; NP_598328
	NP_001104485; NP_001313489; NP_038709
	Wikidata
View/Edit Human	View/Edit Mouse

Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins associate as endogenous substrates to the surface of synaptic vesicles and act as key modulators in neurotransmitter release across the presynaptic membrane of axonal neurons in the nervous system.