SYT11

SYT11
Identifiers
Aliases	SYT11, SYT12, sytXI, synaptotagmin 11
External IDs	OMIM: 608741; MGI: 1859547; HomoloGene: 23120; GeneCards: SYT11; OMA:SYT11 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,885,199 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	88,682,471 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; external globus pallidus; ; lateral nuclear group of thalamus; ; inferior ganglion of vagus nerve; ; postcentral gyrus; ; pars reticulata; ; prefrontal cortex; ; Brodmann area 46; ; pars compacta; ; ventral tegmental area;
	Top expressed in
	motor neuron; ; Rostral migratory stream; ; anterior horn of spinal cord; ; substantia nigra; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; pontine nuclei; ; subiculum; ; medial dorsal nucleus; ; dorsal tegmental nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	clathrin binding; calcium ion binding; syntaxin binding; protein binding; metal ion binding; translation initiation factor binding; ubiquitin protein ligase binding; SNARE binding; protein homodimerization activity; beta-tubulin binding; calcium-dependent phospholipid binding; phosphatidylserine binding;
Cellular component	integral component of membrane; cell junction; synapse; integral component of plasma membrane; synaptic vesicle membrane; membrane; cytoplasmic vesicle; vesicle; phagocytic cup; presynaptic active zone membrane; inhibitory synapse; synaptic vesicle; presynapse; dendritic spine; lysosome; cytoplasm; recycling endosome; postsynaptic density; plasma membrane; cell body; axon; early phagosome; excitatory synapse; neuron projection; terminal bouton; phagocytic vesicle; perinuclear region of cytoplasm; integral component of synaptic vesicle membrane; Schaffer collateral - CA1 synapse; postsynapse; integral component of presynaptic active zone membrane; exocytic vesicle;
Biological process	negative regulation of neurotransmitter secretion; regulation of phagosome maturation; regulation of defense response to bacterium; calcium ion-regulated exocytosis of neurotransmitter; negative regulation of synaptic vesicle endocytosis; negative regulation of membrane invagination; vesicle fusion; protein homotetramerization; negative regulation of clathrin-dependent endocytosis; negative regulation of phagocytosis; positive regulation of protein localization to phagocytic vesicle; plasma membrane repair; response to wounding; negative regulation of clathrin-coated pit assembly; calcium ion regulated lysosome exocytosis; regulation of calcium ion-dependent exocytosis; regulation of dopamine secretion; vesicle-mediated transport; calcium-ion regulated exocytosis; cellular response to calcium ion;
	Sources:Amigo / QuickGO
Orthologs
	23208
	229521
	ENSG00000132718
	ENSMUSG00000068923
	Q9BT88
	Q9R0N3
	NM_152280
	NM_018804
	NP_689493
	NP_061274
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptotagmin-11 is a protein that in humans is encoded by the SYT11 gene.