Isatin

Isatin
Names
	Preferred IUPAC name 1H-Indole-2,3-dione
Identifiers
CAS Number	91-56-5 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	383659
ChEBI	CHEBI:27539 ;
ChEMBL	ChEMBL326294 ;
ChemSpider	6787 ;
DrugBank	DB02095 ;
ECHA InfoCard	100.001.889
EC Number	202-077-8;
Gmelin Reference	165206
KEGG	C11129 ;
PubChem CID	7054;
UNII	82X95S7M06 ;
CompTox Dashboard (EPA)	DTXSID3038694 ;
	InChI InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11) Key: JXDYKVIHCLTXOP-UHFFFAOYSA-N ; InChI=1/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11);
	SMILES O=C2c1ccccc1NC2=O;
Properties
Chemical formula	C8H5NO2
Molar mass	147.1308 g/mol
Appearance	Orange-red solid
Melting point	200 °C (392 °F; 473 K)
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H319, H335
Precautionary statements	P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Isatin, also known as tribulin, is an organic compound derived from indole with formula C₈H₅NO₂. The compound was first obtained by Otto Linné Erdman and Auguste Laurent in 1840 as a product from the oxidation of indigo dye by nitric acid and chromic acids.

Isatin is a well-known natural product which can be found in plants of the genus Isatis, in Couroupita guianensis, and also in humans, as a metabolic derivative of adrenaline.

It looks like a red-orange powder, and it is usually employed as building block for the synthesis of a wide variety of biologically active compounds including antitumorals, antivirals, anti-HIVs, and antituberculars.

The isatin core is also responsible for the color of “Maya blue” and “Maya yellow” dyes.

It is rumored that isatin is a MAOI with dopaminergic properties.