Sea star-associated densovirus

Sea star-associated densovirus (SSaDV) belongs to the Parvoviridae family. Like the other members of its family, it is a single-stranded DNA virus. SSaDV has been suggested to be an etiological agent of sea star wasting disease, but conclusive evidence has not yet been obtained. Further work in 2018 and 2020 re-examined the association between SSaDV and sea star wasting and found no evidence in both the original work and subsequent surveys of sea stars. More recently, densoviruses associated with echinoderms were recognized as forming persistent infections in their hosts and become endogenized within sea star genomic DNA. Densoviruses including SSaDV become more pronounced during sea star wasting progression, but no single strain is associated with sea star wasting disease.