Segundo Frente
| Segundo Frente | |
|---|---|
| Apartment buildings in Mayarí Arriba | |
| Segundo Frente municipality (red) within  Santiago Province (yellow) and Cuba | |
| Coordinates: 20°24′43″N 75°31′43″W / 20.41194°N 75.52861°W | |
| Country | Cuba | 
| Province | Santiago de Cuba | 
| Seat | Mayarí Arriba | 
| Area | |
|  • Total | 540.2 km2 (208.6 sq mi) | 
| Elevation | 180 m (590 ft) | 
| Population  (2022) | |
|  • Total | 40,196 | 
| • Density | 74/km2 (190/sq mi) | 
| Time zone | UTC-5 (EST) | 
| Area code | +53-226 | 
| Website | https://www.segundofrente.gob.cu/ | 
Segundo Frente (Spanish for "Second Front") is a municipality in the Santiago de Cuba Province of Cuba. Located in the northern part of the province, it is centered on the town, and municipal seat, of Mayarí Arriba.