Seizure

Epileptic seizure
Other namesEpileptic fit, seizure, fit, convulsions
Generalized 3 Hz spike and wave discharges in an electroencephalogram (EEG) of a patient with epilepsy
SpecialtyNeurology, emergency medicine
SymptomsVariable
ComplicationsFalling, drowning, car accidents, pregnancy complications, emotional health issues
DurationTypically less than 2 minutes
TypesFocal, generalized; provoked, unprovoked
CausesProvoked: Low blood sugar, alcohol withdrawal, low blood sodium, fever, brain infection, traumatic brain injury
Unprovoked: Flashing lights or colours, unknown causes, previous stroke, brain injury, brain tumor
Diagnostic methodBased on symptoms, blood tests, medical imaging, electroencephalography
Differential diagnosisSyncope, psychogenic seizure, migraine aura, transient ischemic attack
TreatmentLess than 5 min: Place person on their side, remove nearby dangerous objects
More than 5 min: Treat as status epilepticus
Frequency≈10% of people (lifetime risk)

A seizure is a sudden, brief disruption of brain activity caused by abnormal, excessive, or synchronous neuronal firing. Depending on the regions of the brain involved, seizures can lead to changes in movement, sensation, behavior, awareness, or consciousness. Symptoms vary widely. Some seizures involve subtle changes, such as brief lapses in attention or awareness (as seen in absence seizures), while others cause generalized convulsions with loss of consciousness (tonic–clonic seizures). Most seizures last less than two minutes and are followed by a postictal period of confusion, fatigue, or other symptoms. A seizure lasting longer than five minutes is a medical emergency known as status epilepticus.

Seizures are classified as provoked, when triggered by a known cause such as fever, head trauma, or metabolic imbalance, or unprovoked, when no immediate trigger is identified. Recurrent unprovoked seizures define the neurological condition epilepsy.