Selective estrogen receptor modulator
| Selective estrogen receptor modulator | |
|---|---|
| Drug class | |
Tamoxifen, a nonsteroidal triphenylethylene antiestrogen and a widely used drug in the treatment of breast cancer. | |
| Class identifiers | |
| Synonyms | SERM; Estrogen receptor agonist/antagonist; ERAA |
| Use | Breast cancer, infertility, osteoporosis, vaginal atrophy, dyspareunia, contraception, male hypogonadism, gynecomastia, breast pain, others |
| ATC code | G03XC |
| Biological target | Estrogen receptor |
| Legal status | |
| In Wikidata | |
Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen receptors (ERs). Compared to pure ER agonists–antagonists (e.g., full agonists and silent antagonists), SERMs are more tissue-specific, allowing them to selectively inhibit or stimulate estrogen-like action in various tissues.