Sessile serrated lesion
| Sessile serrated lesion | |
|---|---|
| Other names | Sessile serrated polyp (SSP) Sessile serrated adenoma (SSA) |
| Micrograph of a sessile serrated lesion. H&E stain. | |
| Specialty | Gastroenterology |
| Symptoms | Asymptomatic |
| Complications | Colorectal cancer |
| Diagnostic method | Colonoscopy |
| Treatment | Polypectomy |
A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon.
SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC gene.
Multiple SSLs may be part of the serrated polyposis syndrome.