Sex hormone

Sex hormone
Drug class
Estradiol, an important estrogen sex hormone in both women and men
Class identifiers
SynonymsSex steroid; Gonadal steroid
UseVarious
Biological targetSex hormone receptors
Chemical classSteroidal; Nonsteroidal
Legal status
In Wikidata

Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. The sex hormones include the androgens, estrogens, and progestogens. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. Certain polypeptide hormones including the luteinizing hormone, follicle-stimulating hormone, and gonadotropin-releasing hormone – each associated with the gonadotropin axis – are usually not regarded as sex hormones, although they play major sex-related roles.