Sex hormone
| Sex hormone | |
|---|---|
| Drug class | |
| Class identifiers | |
| Synonyms | Sex steroid; Gonadal steroid |
| Use | Various |
| Biological target | Sex hormone receptors |
| Chemical class | Steroidal; Nonsteroidal |
| Legal status | |
| In Wikidata | |
Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. The sex hormones include the androgens, estrogens, and progestogens. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. Certain polypeptide hormones including the luteinizing hormone, follicle-stimulating hormone, and gonadotropin-releasing hormone – each associated with the gonadotropin axis – are usually not regarded as sex hormones, although they play major sex-related roles.