Shiga toxin
| Shiga-like toxin beta subunit | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | SLT_beta | ||||||||
| Pfam | PF02258 | ||||||||
| InterPro | IPR003189 | ||||||||
| SCOP2 | 2bos / SCOPe / SUPFAM | ||||||||
| TCDB | 1.C.54 | ||||||||
| |||||||||
| Shiga-like toxin subunit A | |
|---|---|
| Identifiers | |
| Symbol | Shiga-like_toxin_subunit_A |
| InterPro | IPR016331 |
| SCOP2 | 1r4q / SCOPe / SUPFAM |
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named after Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. Shiga-like toxin (SLT) is a historical term for similar or identical toxins produced by Escherichia coli. The most common sources for Shiga toxin are the bacteria S. dysenteriae and some serotypes of Escherichia coli (shigatoxigenic or STEC), which include serotypes O157:H7, and O104:H4.