Single transverse palmar crease

Single transverse palmar crease
Other namesSimian crease, simian line
Single transverse palmar crease on an infant's hand
SpecialtyMedical genetics

In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases. Although it is found more frequently in persons with several abnormal medical conditions, it is not predictive of any of these conditions since it is also found in persons with no abnormal medical conditions.

This crease is estimated to occur in 1.5-3% of the general population, although it is more common in East Asian and Native American populations.