Slaughter Branch

Slaughter Branch is a stream in northern Franklin County in the U.S. state of Missouri. It is a tributary to Brushy Creek.

The headwaters of the stream are at 38°31′02″N 91°10′22″W / 38.51722°N 91.17278°W / 38.51722; -91.17278 and the confluence with Brushy Creek is at 38°31′02″N 91°07′06″W / 38.51722°N 91.11833°W / 38.51722; -91.11833. The source area for the stream lies just south of Campbellton and Missouri Route 185.

Slaughter Branch most likely derives its name from George Slaughterback, a pioneer citizen.